Scientific Source #35 – Peer-Reviewed Article

“In mammals, egg activation is initiated by multiple cytosolic Ca(2+) transients (Ca(2+) oscillations) that are triggered following delivery of a putative sperm factor from the fertilizing sperm. The identity of this ‘sperm factor’ thus holds much significance, not only as a vital component in creating a new life, but also for its potential therapeutic and diagnostic value in human infertility”35

35Kashir, J., Nomikos, M., Swann, K., & Lai, F.A., PLCζ or PAWP: revisiting the putative mammalian sperm factor that triggers egg activation and embryogenesis, Mol Hum Reprod, 2015, 21(5):383-8,

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